The most common symptom of CP is vaginal bleeding, which is often profuse and painless. Diagnosis involves a combination of clinical symptoms, serology, and ultrasound. Other predisposing factors are previous caesarean delivery, cervical surgery, endometritis, use of an intrauterine device and in-vitro fertilization (IVF). Although the aetiology of CP is unknown, a history of dilation and curettage in a previous pregnancy has been identified as risk factors in nearly 70% of cases. CP incidence ranging between one in 1000 and one in 18,000 of all pregnancies and 1% of all EP. Non-tubal EPs account for less than 10% of all EPs, though their overall incidence has been increasing in recent years. Further prospective studies on larger samples are needed to define therapeutic protocols for CP management.Ĭervical pregnancy (CP) is a rare form of ectopic pregnancy (EP) in which the embryo implants and grows inside the endocervical canal. Hysteroscopy, alone or in combination with MTX, may provide a greater effect on the descent of βhCG, leading to a reduction of the hospitalization stay, decreasing costs and period for attempt pregnancy. Conclusions: Many therapeutic approaches are effective for CP treatment. The onset of a spontaneous pregnancy at the normal implantation site occurred after five months in one case treated by hysteroscopy. Serum βhCG levels had a faster drop the day after hysteroscopy than post medical management. Serum β-hCG levels become undetectable in a range of 15–40 days after hysteroscopic management after medical treatment it become undetectable after 35 days.

No complications, such as vaginal bleeding, were recorded in the other cases. Haemorrhage was controlled by a second hysteroscopic procedure. Results: In one patient treated by hysteroscopy alone it occurred a profuse vaginal bleeding with necessity for blood transfusion. One case with βhCG levels < 5000 mUi/mL was treated using MTX combined to Mifepristone and Misoprostol.

Four patients, with βhCG levels > 5000 mUi/mL were managed by hysteroscopy, with or without a previous systemic Methotrexate (MTX).

Five patients with a diagnosis of CP, hemodynamically stables and managed conservatively between 20 at the Institute of Child and Maternal Health Burlo Garofolo in Trieste, Italy, were included. Materials and Methods: This is a retrospective observational case series. The aim of this study is to evaluate the efficacy of hysteroscopic management in early CP in order to preserve future fertility. Although many treatment approaches are disponible, the most effective is still unclear. Early diagnosis is essential in order to allow conservative medical and surgical treatments. Background and objectives: Cervical pregnancy (CP) is a rare form of ectopic pregnancy (EP) in which the embryo implants and grows inside the endocervical canal.

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